NAM Resources for Scientists

Photo by Zhu Difeng
Overview
For those who are seeking funding for new approach methodologies (NAMs)-related research, or simply want to learn more about the use of NAMs in science, below is a curated list of third-party links to funding opportunities, searchable databases, and other informational resources and webinars.
US Funding Opportunities
- Alternatives Research & Development Foundation (ARDF) – Annual Open Grant Program
- Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) – International Global 3Rs Awards Program
- International Foundation for Ethical Research (IFER) – Graduate Fellowships for Alternatives to the Use of Animals in Science
- Johns Hopkins Center for Alternatives to Animal Testing (CAAT) – Alan and Helene Godlberg In Vitro Toxicology Grant
- National Cancer Institutes (NCI) – Cancer Tissue Engineering Collaborative
- National Center for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) – yearly International 3Rs Prize
- National Institutes of Health (NIH) Complement Animal Research in Experimentation (Complement-ARIE) – Common Fund Program
- People for the Ethical Treatment of Animals (PETA) Science Consortium International e.V., the Physicians Committee for Responsible Medicine (PCRM), and the Alternative Research & Development Foundation (ARDF) – Recombinant Antibody Challenge
- Physician Committee for Responsible Medicine (PCRM) – Human Advanced In Vitro Model Initiative (HUMAIN)
Other Resources
- 3Rs Collaborative MPS Hub, including:
- A searchable Tech Hub for commercially available MPS systems
- A searchable Publication Hub, a centralized resource for peer-reviewed research on commercially available MPS models
- Animal Welfare Information Center (AWIC) – Alternatives Literature Search service and Meeting the Requirements of the Animal Welfare Act Workshop
- Certara Non-Animal Navigator
- EPIC Webinar Series on the Use of NAMs in Risk Assessment
- FDA’s Alternative Methods Forum Series
- FDA’s Innovative Science and Technology Approaches for New Drugs (ISTAND) Pilot Program
- ICCVAM recommended protocols for specific test methods
- NAM Journal
- NC3Rs’ New Approach Methodologies Resource Library, including:
- NAMS portfolio with publications about successful NAMs research and development
- Current NAMs products
- NAMs webinars
- Collaboration platform
- NICEATM Alternative Methods Resource Center, including:
- ALTBIB access to PubMed citations for users seeking information on alternatives
- How to approach NAMs validation
- ICCVAM recommendations for approaches to replace and reduce animal use
- Currently accepted alternative methods in the United States
- Testing Regulations and Guidelines
- Tracking System for Alternative Methods (TSAR)
- NTP’s Integrated Chemical Environment (ICE) data sets for targeting toxicity endpoints
- OECD Test Guidelines
- PCRM’s NAM Use for Regulatory Application (NURA) Training and NAMs within TSCA Training
- Replacement Checklist for researchers, funding review panels, ethical review bodies, and journal editors
- Replacing Animal Research Guide
- TedTalk: Body parts on a chip
- Wyss Institute’s organ-on-a-chip publications
Replacing Animals with Nonanimal Methods
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