Program Term Archive

Replacing Animals with Nonanimal Methods

NAMS: Advancing Science and Reducing Animal Use in Laboratories

Animals in Laboratories

A brochure developed by AWI for high schoolers. Many scientists and animal advocacy groups have a shared goal of reducing or eliminating the use of animals in laboratories as nonanimal...

Where NAMs Fit in the Current Research Landscape

Animals in Laboratories

The rate of new approach methodologies (NAM) development varies among the different scientific purposes for which animals are used. According to a Scientific American article, we are much closer to...

NAM Techniques: In Chemico, In Vitro, In Silico

Animals in Laboratories

New approach methodologies (NAMs) can be divided into three broad categories, in chemico, in vitro, and in silico. In chemico is generally the simplest NAM technique, in which the chemical...

NAM Resources for Scientists

Animals in Laboratories

For those who are seeking funding for new approach methodologies (NAMs)-related research, or simply want to learn more about the use of NAMs in science, below is a curated list...

NAM Resources for Policymakers

Animals in Laboratories

For those seeking to learn about existing policies pertaining to the development, validation, and use of new approach methodologies (NAMs), below is a curated list of third-party links to relevant...

Replacing Animals with Nonanimal Methods

Animals in Laboratories

While generally the absolute replacement of animals with nonanimal methods is more challenging than refinement or reduction, just because it will be challenging does not mean it is not worthwhile....

AWI Joins Partnership to Advance Nonanimal Experimentation Methods

Animals in Laboratories

AWI has joined the Validation & Qualification Network (VQN), a public-private partnership to foster the development and use of new approach methodologies (NAMs)—innovative techniques that can help reduce and replace animals...

NIH Announces Major Change in Funding Priorities

Animals in Laboratories

In line with its recently announced initiative to prioritize human-based research (see AWI Quarterly, summer 2025), the NIH announced in July that moving forward, all new calls for funding from the agency, known...

Replacing Animals in Experimentation: Where We Are, Where We’re Going

Animals in Laboratories

Experiments on animals (“in vivo” experiments) have long been the norm for learning about human health and disease, because testing on live animals enables researchers to investigate how chemicals, drugs,...

AWI Statement on Trump Administration’s Plan to Reduce Animal Experimentation Amid Attack on Science

Press StatementJune 18, 2025Animals in Laboratories

The Animal Welfare Institute (AWI) applauds recent announcements by the National Institutes of Health and the US Food and Drug Administration about their plans to reduce the use of animals in research and testing....